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The following information has been compiled from publicly available sources, StratCom does not assume any responsibility for the accuracy or the authenticity of the information and StratCom cannot be held liable for errors.

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Molecular Biology — January 2002

Affymetrix launched the GeneChip Human Genome U133 Set of 2 microarray chips. HG-U133 is the first commercial array set to use the publicly available draft of the human genome.

Beckman Coulter, Inc. has introduced the CEQ 8000 Genetic Analysis System, which automates and integrates the majority of genetic analysis functions into one system. With one gel, one array and one software platform, users can perform DNA sequencing, heterozygote detection, confirmatory sequencing, mutation analysis, allele identification, SNP scoring, microsatellite instability and AFLP fingerprinting. The system's configuration of eight capillary arrays interfaces with 96-well plate formats.

Genzyme Molecular Oncology has discovered RNASEL, a susceptibility gene influencing the genetic predisposition to prostate cancer. Germline mutations in the ribonuclease L gene show linkage with HPC1 prevalent within prostate cancer families linked to the hereditary prostate cancer (HPC1) region

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Pel-Freez Clinical Systems, LLC has signed an exclusive distribution agreement with StemCell Technologies, Inc. whereby Pel-Freez has exclusive rights to market and sell specific RosetteSep products to the US HLA typing market. The RosetteSep technique enriches circulating lymphocytes directly from samples of whole blood.

ProteEx, Inc. is developing two-dimensional polyacrylamide gel electrophoresis technology to provide proteomic analysis of breast nipple aspirate fluid protein patterns from patients diagnosed with breast cancer.

Third Wave Technologies Inc. has launched four new Invader DNA analyte-specific reagents for ApoE (C112R), ApoE (R158C), GPIIIa (PLA1/A2) and GPIa (C807T). These ASRs feature a biplex format, which allows for the simultaneous detection of all variations for each single nucleotide polymorphism in a single well.

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